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Hurt Group - GrouplearderAcademic Training and Positions

  • 1974 - 1979 Student of biology and chemistry at the University of Regensburg
  • 1980 - 1983 PhD studies at the University of Regensburg
  • 1984 - 1986 Postdoc at the Biocenter, University of Basel, Switzerland
  • 1987 - 1994 Group Leader at the EMBL Heidelberg in the Cell Biology Program
  • since   1995 Full Professor (C4) at Heidelberg University
  • 2003 - 2005 Director of the Heidelberg University Biochemistry Center (BZH)
Groupleader Prof. Dr. Ed C. Hurt
Hurt Group - GrouplearderPrizes, Awards & Academy memberships

  • 2015 Eduard Buchner Prize (read more ...)
  • 2007 Feldberg Prize (read more ...)
  • 2001 Gottfried Wilhelm Leibniz Prize
    (read more ...)
  • 1984 Kulturpreis Ostbayern (PhD award)
  • 2007 member of ACADEMIA EUROPAEA
  • 2003 member of LEOPOLDINA
  • 1994 member of EMBO

International recognition

For Publication ranking see (laborjournal.de)

Scopus citation overview: since 1997 a total of 97 cited publications with a total of 4579 citations

Hurt Group - Grouplearder10-Year-Track-Record  (Top Publications)

Dieter Kressler, Gert Bange, Yutaka Ogawa, Dagmar Pratte, Bettina Bradatsch, Daniela Roser, Jun Katahira, Irmgard Sinning und Ed Hurt: Coordinated nuclear transport and assembly of functionally related ribosomal proteins onto nascent ribosomes by a common import adaptor
.Science Vol. 338 no. 6107, 666-671 (2012).

Stefan Amlacher, Phillip Sarges, Dirk Flemming, Vera van Noort, Ruth Kunze, Damien Devos, Manimozhiyan Arumugam, Peer Bork and Ed Hurt: Insight into structure and assembly of the nuclear pore complex by utilizing the genome of a eukaryotic thermophile
.Cell 146, 277-289 (2011).

Cornelia Ulbrich, Meikel Diepholz, Jochen Baßler, Dieter Kressler, Brigitte Pertschy, Kiki Galani, Bettina Böttcher and Ed Hurt: Mechanochemical Removal of Ribosome Biogenesis Factors from Nascent 60S Ribosomal Subunits
.Cell 138, 911-922 (2009).

Dirk Flemming, Philipp Sarges, Philipp Stelter, Andrea Hellwig, Bettina Boettcher and Ed Hurt: A toxic nucleoporin mutant induces abarrent nucleoporin foci in the cytoplasm
.J. Cell Biol. 185, 387-396 (2009).

Alwin Köhler, Maren Schneider, Ghislain G. Cabal, Ulf Nehrbass and Ed Hurt: Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export
. Nature Cell Biology 10, 707-715 (2008).

Philipp Stelter, Ruth Kunze, Dirk Flemming, Dominic Höpfner, Meikel Diepholz, Peter Philipsen, Bettina Böttcher and Ed Hurt: Molecular basis for the functional interaction of dynein light chain with the nuclear pore complex
.Nature Cell Biology 9, 788-769 (2007).

Ghislain Cabal, Susana Rodrigez-Navarro, August Genevesio, Jean-Christophe Olivo-Marin, Christophe Zimmer, Olivier Gadal, Frank Feuerbach-Fournier, Annick Lesne, Henri Buc, Ed Hurt* and Ulf Nehrbass* (*corresponding authors): Molecular Analysis of SAGA Mediated Gene Gating In Yeast
.Nature 441, 770-773(2006).

Thorsten Schäfer, Bohumil Maco, Elisabeth Petfalski, David Tollervey, Bettina Boettcher, Ueli Aebi and Ed Hurt: A round of phosphorylation/de-phosphorylation triggers maturation of the pre-ribosomal 40S subunit
.Nature 441, 651-655 (2006).


Fields of research interest and reviewer activities

Nuclear pore complex, nucleocytoplasmic transport, transcription-coupled mRNA export, ribosome biogenesis and export nuclear envelope organization, nucleolus, sumoylation, ubiquination, transcription, chromatin organization/modification, membrane biogenesis. Over the past 10 years I served as reviewer for a number of life science journals including Nature, Science, Cell, Mol. Cell, Nature Cell Biol., J. Cell Biol., Genes Dev., EMBO J., MBC and MCB.

Press releases
Reinhart-Koselleck-Projekt für Heidelberger Biochemiker Ed Hurt (read more ... )



Susana Rodriguez-Navarro, Tamàs Fischer, Ming-Juan Luo, Oreto Antunez, Susanne Brettschneider, Jose E. Perez-Ortin, Robin Reed, and Ed Hurt: Sus1, a functional component of the SAGA histone acetylase complex and the nuclear pore-associated mRNA export machinery
.Cell 116, 75-86 (2004).

Tamas Fischer, Susana Rodriguez-Navarro, Elmar Schiebel and Ed Hurt: Yeast centrin Cdc31 is linked to the nuclear mRNA export machinery
.Nature Cell Biol.6,840-848 (2004).

Malik Lutzmann, Ruth Kunze, Andrea Buerer, Ueli Aebi and Ed Hurt: Modular Self-Assembly of a Y-Shaped Multiprotein Complex from Seven Nucleoporins
.EMBO J. 21, 387-397 (2002).

Katja Sträßer, Seiji Masuda, Paul Mason, Jens Pfannstiel, Marisa Oppizzi, Susana Rodriguez-Navarro, Ana G. Rondón, Andres Aguilera, Kevin Struhl, Robin Reed, and Ed Hurt: TREX is a conserved complex coupling transcription with mRNA export
.Nature 417, 304-308 (2002).

Katja Sträßer and Ed Hurt: The splicing factor Sub2p interacts directly with the mRNA transport factor Yra1p and is required for nuclear mRNA export
.Nature 413, 648-652 (2001).

Jochen Baßler, Paola Grandi, Olivier Gadal, Torben Lessmann, David Tollervey, Johannes Lechner, and Ed Hurt: Identification of a 60S pre-ribosomal particle that is closely linked to nuclear export.
.Mol. Cell 8, 517-529 (2001).

Prof. Dr. Ed C. Hurt
Heidelberg University
Biochemistry Center (BZH)
Im Neuenheimer Feld 328
D-69120 Heidelberg

Phone: +49 (0)6221 544173
Fax:     +49 (0)6221 544369


Hurt Group - GrouplearderCareers of supervised graduate and postdoc students  

Yoshitaka Matsuo (former postdoc 2013)
- Assistant Professor at Tohoku University, Japan;

Dieter Kressler (former postdoc 2009)
- Professor at Université Fribourg, Switzerland;

Alwin Köhler (former postdoc 2009)
- Junior Group Leader at Max F. Perutz Laboratories,
Vienna, Austria;

Vikram Panse (former postdoc 2006)
- Principal investigator at ETH Zurich, Switzerland;

Tamás Fischer (former postdoc 2006)
- Junior Group Leader, BZH, University of Heidelberg ;

Tracy Nissan (former postdoc 2004)
- Junior Group Leader at Umea University, Sweden;

Susana Rodriguez-Navarro (former postdoc 2004)
- Principal investigator at CIPF, Valencia, Spain;

Katja Sträßer (former PhD student 2003)
- Principal investigator at the Gene Center, Munich, Germany;

Helge Großhans (former PhD student 2002)
- Group Leader at Friedrich Miescher Institute Basel, Switzerland;

Markus Kuenzler (former PhD student 2001)
- Senior Scientist at the ETH Zürich;

Symeon Siniossoglou
(former PhD student 2000)
- Principal investigator at CIMR, Cambridge, UK;

Isabelle Sagot (former postdoc 2001)
- Senior researcher at CNRS/Université Bordeaux, France;

Olivier Gadal (former postdoc 2000)
- Principal investigator at CNRS/Université Toulouse, France;


George Simos (former postdoc 1998)
- Professor at University of Thessaly, Larissa, Greece;

Buket Kosova (former PhD student 1999)
- Senior researcher at Ege University Izmir/Turkey;

Helena Santos-Rosa (former postdoc 1998)
- Research associate at University of Cambridge/The Gurdon Institute, UK;

Jun Katahira (former postdoc 1998)
- Associate Professor at University of Osaka/Japan

Stefan Hannus (former PhD student 1998)
- Intana Biosciences Martinsried

Nikolaus Schlaich (former postdoc 1997)
- Assistant Professor at RWTH Aachen, Germany;

Thierry Berges (former postdoc 1996)
- Professor at UFR Sciences, Poitiers, France;

Ulf Nehrbass (former PhD student 1994)
- CNRS research director of the Institute Pasteur, Paris, France and Director of Pasteur Institute in Seoul, Korea;

Valérie Doye (former postdoc 1994)
- Group Leader and research director at the Curie Institute Paris, France;

Ralf Jansen (former PhD student 1993)
- Full Professor at the Interfaculty Institute of Biochemistry (IFIB), University of Tuebingen, Germany.